Hypertrophic cardiomyopathy (HCM) is an autosomal dominant disease characterized by left and/or occasionally right ventricular myocardial hypertrophy in the absence of dilatation of its cavity and causes of muscle hypertrophy. Numerous investigation are made in anatomy and geometry of the left ventricle study at patients with HCM by magnetic resonance imaging (MRI). MRI is considered to be the optimal method for monitoring patients with HCM, since the technique accurately determines both the localization and the magnitude of hypertrophy, and in addition, evaluates the function of the ventricles. Using a 17-segment model published by the American Heart Association (AHA), the method allows one to reliably verify the localization of the pathological process and is especially suitable for characterizing phenotypic expression of HCM. The delayed-contrast MRI technique is highly sensitive in visualizing fibrotic lesions in the left ventricular myocardium, which correlates with histological data.
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- Vladimir N. Makarenko, Dr. Med. Sc., Professor, Head of Department, ORCID
- Ol'ga Yu. Dariy, Radiologist, ORCID